Medicine

Primary care providers (physicians, nurse practitioners, physician assistants) make decisions on a daily basis regarding treatment for musculoskeletal problems, including referrals to orthopedic surgeons and other specialists. Despite the large number of patients presenting with musculoskeletal complaints, primary care providers often feel poorly educated about how to assess and manage these conditions.

Written by expert orthopedic, physical medicine and pain management specialists at major Harvard teaching hospitals, the second edition of Principles of Orthopedic Practice for Primary Care Providers represents a high-yield and succinct resource on the assessment and management of musculoskeletal conditions. Chapters overview specific body parts, typical presentations of disease, options for diagnostic testing, treatment paradigms, and anticipated outcomes of management both in the primary care setting and following specialist consultation. The text offers suggested pathways for working up and treating these problems with an emphasis on when referral to a specialist, or surgical intervention, is needed.

While all previous chapters have been fully revised, this edition also includes nine brand new chapters, including chapters on pain management, hip-spine syndrome, adult spinal deformity, sports-related injuries, and cost and quality in musculoskeletal care.

This heavily revised third edition concisely covers the latest evidence-based treatment strategies for urinary incontinence and prolapse. Chapters cover methodologies relevant to continence procedures, prolapse management, and potential complications. New topics discussed include Colpocleisis, principles associated with managing Mesh complications and the Mirabegron mechanism.

Urogynecology: Evidence-Based Clinical Practice 3rd Edition is a vital how-to guide, which is ideal for junior registrars assigned to work in a urogynecology department, as well as for those with no previous formal urogynecological training seeking to develop their understanding of the subject.

The book is intended to serve as a practical guide to effective ear examination. Learning to perform otoscopy is not easy because the external auditory canal is obstructed by cerumen, otorrhea can be present, and the tympanic membrane is sometimes only partially visible. In children, it is even more difficult because of the narrow ear canal, the alignment of the tympanic membrane, and the restlessness of the child. 

Uncertainty in diagnosis can lead to overtreatment, as in the case of acute otitis media and unnecessary prescription of antibiotics. On the other hand, delay in diagnosis may lead to severe complications such as mastoiditis, meningitis and brain abscess in case of overlooked middle ear cholesteatoma. 

This textbook aims to facilitate learning through a wealth of full color otoscopic pictures and is divided into chapters that cover the major otologic pathologies. The volume includes images related to cochlear implants and bone conduction devices, along with the images of the major surgical procedures or conditions associated with them. It also helps the reader to identify the conditions in which surgical intervention is mandatory. 

Given its didactic approach, this guide will be an invaluable resource for medical students and residents in otolaryngology, and in paediatrics and general medicine alike.

This book aims to teach the skills for assessing the quality of a medical article.  It focuses on problems and pitfalls that may interfere with the validity of an article so that readers know what problems to look for and how to tell if an article has successfully addressed them.  It focuses on concepts rather than formulas.  In each chapter, one article will be analyzed to illustrate a particular concept, demonstrating when to look for that pitfall, how to recognize it, what effect it would have on results, and how to tell if an author has successfully mitigated the pitfall.

Written with clarity and precision, this invaluable resource ensures that readers develop a deep understanding of the critical elements that underpin the quality of medical literature. Each chapter presents a specific concept and employs a practical approach, utilizing the analysis of a real-world medical article to illustrate the concept in action. By dissecting the research, readers learn to identify common pitfalls, recognize their influence on the results, and determine whether the author has effectively addressed them.

By exploring topics such as research methodology, bias detection, and result interpretation, Problems and Pitfalls in Medical Literature empowers readers to go beyond a superficial understanding of articles and critically evaluate their reliability and relevance.

Taking a truly interdisciplinary approach to the topic, Functional Limb Salvage is a ready reference for all clinicians and surgeons treating this patient population, including plastic, vascular, orthopedic and podiatric surgeons and their support staff. 

The content of this text is focused on defining and expanding upon the importance and, more specifically, the intricacies of the multidisciplinary team approach. Although this is often touched upon or cited as an integral aspect of care, there are only sparse descriptions of the interplay of multiple team members in concert with the care of this challenging patient population. 

This comprehensive text opens with definitions, demographics, epidemiology, pathophysiology and etiology of the limb salvage patient population, whether due to infection, ischemia or deformity. The multidisciplinary team itself is then outlined, from the who, when and where of the intervention to the role of the individual clinicians themselves; from vascular and plastic surgeons to podiatric and orthopedic surgeons, multiple medical specialties, and with thorough attention to the integral support staff of NPs, PAs and many others. History and assessment are then discussed as a prelude to both conservative and surgical treatments, including wound healing optimization, orthotics and prosthetics, skin grafting, amputation, bioengineered tissue and more. A final chapter on innovation and landmark publications rounds out the presentation.

Since the first edition of this book in 2012, the field of molecular pathology has expanded exponentially. The advent of complete cancer genome sequencing, new diagnostic molecular tests, and biomarkers for targeted therapy and immunotherapy have demonstrated the importance of molecular tools both in patient care and in the practice of pathology. Furthermore, the development of many new molecular technologies has revolutionized the practice of modern pathology. The rapid growth of this field has led to an expansion of knowledge of molecular processes and many more clinical applications in our daily practice of surgical pathology. Thus, this updated second edition of Molecular Surgical Pathology aims to serve as the best available “quick reference” for pathologists, oncologists, geneticists, primary care physicians, and other medical professionals with an interest in this specialty.

Molecular Surgical Pathology 2^nd Edition focuses on the practical utility of molecular techniques and on molecular biomarkers for the practicing surgical pathologist. The emphasis is on the impact of molecular pathology for tumor classification, diagnosis and differential diagnosis, as well as its implications for patient management and personalized care. This concise overview of molecular surgical pathology and molecular classification of tumors of different organ sites will help not only practicing physicians, but also those in training, including residents and fellows in various disciplines.

This book, now in an extensively revised second edition, reviews the evidence relating to the mechanisms, clinical efficacy, safety/toxicity, and clinical application of tooth whitening techniques and materials. All clinical techniques are profusely illustrated step by step. The book is divided into four parts, the first of which explains how tooth whitening with peroxides works and examines the overall safety of peroxides and potential complications. The findings of clinical trials with peroxide-based materials for clinical practice are then examined, with discussion of a wide range of issues in at-home whitening and in-office whitening. The third part focuses on the techniques of enamel microabrasion and resin infiltration, which entail removal of a microscopic layer of enamel and may be used to improve tooth color either alone or in combination with peroxides. The concluding part includes a variety of informative clinical cases using combined bleaching and restorative techniquesfor discolored teeth. Tooth Whitening — An Evidence-Based Perspective will be of interest for dentists, dental hygienists, dental assistants, and others with an interest in the subject.

The book describes the experience of four Social Dreaming Matrices held online between March and May 2020, during the first lockdown caused by the Covid 19 emergency. The pandemic isolated us and imposed prolonged contact with ourselves and our solitary thoughts. Against this backdrop, there was hope for change, a desire for a different kind of sociability and different forms of intimacy. On the basis of this evidence, our research supports the shift "from experiencing trauma to reacting to trauma", looking at a collective traumatic experience not only as something to be overcome but as an opportunity for a transformation that changes our mental schemes in relation to the external context. We have identified Social Dreaming as a privileged technique to overcome a collective traumatic experience, supporting its elaboration through collective feelings, new connections between intuition and rational thought, the discovery of community meanings. The authors's thesis is that the much-needed transition from 'magical thinking' to 'transformative thinking' takes place in a setting that is able to contain the anxieties of life's transitional phases, supporting the creation of new rituals and new   social bonds and sustaining the passage from “me” to a “wider we”.

The minimally invasive approach in emergency and general trauma surgery is a key aspect of both scenarios. This book, the first comprehensive manual in the field, takes a global view of the subject and deals with it in depth, ranging from the historical perspective to the pathophysiological and therapeutic aspects in the various body compartments.

Thanks to its user-friendly approach, this book will be a useful tool in the daily clinical practice of surgeons, doctors, anesthetists and nurses; thanks to its up-to-date review of the literature, it will remain relevant for several years. Finally, the participation of world opinion leaders in the field guarantees the comprehensive and scientific soundness of the work.

This book aims to highlight the importance of the development of health conditions and demand for the application of noninvasive mechanical ventilation (NIMV) outside the intensive care units (ICUs); the diversification of possible scenarios outside the ICUs; the need to establish references that consolidate this phenomenon and the healthcare organizations models.

Although the literature that clearly determine the indications and aids on the use of NIMV is considerable, this volume, pointing out the diversity of different healthcare models to define how to organize NIMV outside the ICUs, shed a light and bring a clear benefit to the scientific community involved.

The book is structured in eleven main sections analyzing the epidemiology and trends for NIMV healthcare models and determining factors for these models outside ICUs.

In June 2021, Doctor and Patient decided that time had come to surgically implant two six-inch-long metal alloy spikes all the way through Ben’s brain. It was felt that the medications Ben was taking to control his Parkinson’s disease had become unmanageable.

Back then, Ben was taking about 20 different pills a day. Each pill, if it absorbed properly, would activate the dopamine pathways in his brain and induce uncontrollable writhing movements that would last for about an hour. He would then get about 20 minutes where he’d feel somewhat normal before the slowness and tremor kicked in again. So, he’d take another pill and the cycle would repeat.

After months of adjusting his medication and finding just the right settings on his deep brain stimulator, it was decided, for the first time ever in a clinical trial in North America, to flip on the adaptive settings.

This is the story of how that decision was made and what happened next.

At present, there is minimal and misleading knowledge of gastrointestinal dysfunction in Parkinson's disease among primary neurologists and gastroenterologists. This book reviews our current understanding of the GI involvement in PD, as many experiments suggest that the gut might be the site where the disease starts. Also discussed is how the gut dysfunction causes symptoms from the top (mouth) to the bottom (anal canal), and because of their frequency and severity, they contribute to disease progression and disability. In addition, the book covers the negative effects of small intestinal bacterial overgrowth (SIBO) and of a frequently silent stomach infection by Helicobacter pylori infection on the absorption of antiparkinsonian drugs, in turn causing motor fluctuations and inadequate treatment response.

The Gut in Parkinson's Disease serves as a bridge between patients, their movement disorders specialists, and other health care providers who currently provide compartmentalized and at times conflicting care for such needy patients. The book distills the clinical and research experience of the author, who -as a Clinical Professor of Medicine (Gastroenterology) at Stanford University School of Medicine over the past 20 years- managed hundreds of patients with Parkinson’s Disease suffering from gut manifestations.

This book provides state of the art imaging and serves as a reference standard for anyone wanting to begin or improve their post mortem imaging in children. Divided into three parts, the book covers imaging principles and techniques, interpretation of post mortem imaging, and guidance on which imaging technique to use for which clinical scenarios.

This is an ideal book for researchers and clinical hospital staff using post mortem imaging for children, including pathologists, radiologists, radiographers, technicians, mortuary staff, fetal medicine & obstetricians, ITU staff, forensic imaging staff and pathologists.

Practical in approach and utilizing a systematic approach in the assessment of the fetal heart based on the recommendations of the leading societies

Comparison of line drawings, still ultrasound images and videos consistent with major society recommendations. Extended views for detailed fetal echocardiography will also be addressed

Key prognostic findings will be emphasized with discussion of the obstetric management of affected fetuses

“New” genetics including NIPT and array included

This atlas provides a practical, well-structured and up-to-date guide to the spectrum of corneal disease, diagnostic modalities and relevant therapies. Throughout the atlas, high quality pictures covering each topic are included to utilize a hands-on format with less text and more visual examples. Concise knowledge of common corneal disease for everyday use is presented to ensure that the information can be quickly and easily applied. 

The Atlas of Corneal Disease, Diagnostics and Therapies allows readers to readily compare a finding at the slit-lamp with the book’s illustrations and come to a probable diagnosis for their patients. Students, residents, fellows and ophthalmologists in hospital settings and/or in private practice with a cornea subspecialty or training towards this area will find this atlas to be an indispensable resource in their daily clinical work.

The book offers a comprehensive overview of the latest developments in facial plastic surgery by combining ENT and facial plastic surgery disciplines. The volume is divided into 8 parts and covers all aspects of the topic, from the structure of the face to facial anesthesia and acupuncture. It provides detailed explanations on how to achieve the best outcomes using rejuvenation techniques such as fillers, neurotoxins, suture lifts, and mesotherapy. These techniques will be discussed in detail to achieve cosmetic surgical excellence. This book is an invaluable tool for ENT practitioners, facial plastic surgeons, and plastic surgeons interested in staying up-to-date with the latest techniques and products in facial plastic surgery.

The primary aim of this book is to provide clinicians with the essential knowledge and theoretical foundation needed to perform digital EEG and integrate quantitative EEG (qEEG) into routine clinical practice. Readers will gain a clear understanding of the principles behind qEEG and learn how to apply some of the most widely used numerical tools for EEG analysis.

This work spans a broad spectrum—from the theoretical underpinnings of EEG biosignals to the practical application of numerical methods in real clinical cases. It is structured as a progressive journey: beginning with the origins of EEG signals, advancing through the mathematical foundations of analytical tools, and culminating in the numerical analysis of actual clinical scenarios. In this way, clinicians, including residents, will become familiar with these powerful techniques, grasp their relevance to human pathology, and acquire the skills to implement their own analytical toolbox.

Over the past few decades, the field of qEEG has expanded significantly, with numerous mathematical methods being developed. However, these tools are still rarely used in everyday clinical settings. This gap is often due to a lack of awareness and confidence among clinicians, as well as the perceived complexity of the methods. Drawing from personal experience, the author emphasizes that these tools are highly effective in routine practice and aims to share this insight with the broader neurophysiological community and allied professionals.

Despite its rigorous approach, the book is rich in clinical examples and EEG recording procedures, making it both practical and accessible.

This book aims to serve as an invaluable resource, fostering knowledge exchange and innovation in interventional radiology, with a primary focus on advancing the treatment landscape for malignant bone tumors and embracing complexity with innovative solutions.

Readers are guided through the fundamental understanding of how malignant bone tumors manifest and how precise diagnostic imaging plays a pivotal role in their early detection and characterization.  

The book delves into innovative approaches for securing bone integrity and presents cutting-edge strategies in treating spinal lesions, emphasizing the integration of vertebral implants. Furthermore, the potential of minimally invasive techniques is unveiled, with the introduction of steerable RF devices in bone treatments. Cryoablation , Irreversible Electroporation, HIFU and Embolization techniques in tumor management are also showcased.

Complex cases with tips and tricks and combined treatments complete the book's contents. By addressing the most challenging and intricate scenarios and by emphasizing the importance of interdisciplinary strategies, experts share their experiences.

The book gives an accurate overview of the requirements for modern oncological care, where radiologists, radiotherapists, oncologists, and hematologists collaborate to achieve the best possible patient's care.

This book, in its 2nd edition, is a collection of cases with challenging diagnosis, in which nuclear medicine examinations have been particularly helpful for the clinicians to perform the final diagnosis or to follow-up the patient. The cases selected are primarily in patients with neurodegenerative disorders, epilepsy and brain tumors. Authors have been selected from internationally recognized experts in the field of Neuroimaging in neurology. All authors have large experience as clinicians and as teachers within the Nuclear Medicine community.

The volume includes cases related to emerging topics such as theranostics for brain tumors and new emerging scenarios for brain PET imaging in the era of Alzheimer’s disease modifying drugs.

The book is intended for nuclear medicine specialists as well as clinicians to provide guidance in the interpretation of neurology cases in the clinical settings, particularly with regards to correct approach to the interpretation of diagnostic imaging procedures.

Minimally invasive cosmetic and aesthetic rejuvenation procedures are extremely popular and injecting dermal fillers is now widespread among dermatologists and plastic surgeons. Unfortunately, most books pursue a broad approach to injections for the whole integument or multiple therapeutic modalities, or are too focused on fillers, whereas the data confirms that most patients receive combination treatments with injectables for facial rejuvenation, following a more holistic approach.

Expressly careful to avoid regional, specialty-specific, company or product-based bias, and written by contributors  with a sound clinical and scientific background, this book shares substantial expertise and evidence-based data. A significant portion of the content is devoted to the anatomy, prevention, treatment and management of adverse events and complications after infections, the goal being to promote safe and effective treatment outcomes. As such, Injections in Facial Aesthetic Medicine is a fundamental, complete guide by key  international experts, that will be highly vaued to both novice and experienced professionals in dermatology and plastic surgery who deal with cosmetic procedures in their day-to-day clinical practice.

This groundbreaking volume offers a wealth of practical insights into oral health, oral diseases, and effective daily oral care routines, empowering readers to take proactive control of their oral health. Drawing on the expertise of over 80 contributors from around the globe, it provides a genuinely international perspective through 142 concise chapters organised into sixteen thematic sections.

Presented in a user-friendly Q and A format, the book offers clear and accessible explanations to guide readers through essential topics with ease and confidence. Starting with the history of dentistry and the global burden of oral disease, the volume examines the anatomy and function of maxillofacial structures, orofacial pain, dental trauma, and a wide range of disorders affecting the teeth, gingiva, and jawbones. It covers non-neoplastic soft tissue conditions, as well as benign and malignant tumours of the oral cavity, jaws, and salivary glands, and emphasises the vital link between oral and systemic health. Additional sections introduce key diagnostic tools, treatment approaches, pharmacological therapies, at-home oral care strategies, and important insights into family dentistry.

This volume serves not only as a vital resource for the general public but also as an effective instrument for patient education in clinical settings, and a valuable addition to academic, public, and healthcare libraries worldwide.

Step into the fascinating world of medical history with the second edition of Curiosities in Medicine: Alphabetically, now featuring 20 new chapters, for a total of 100 captivating stories! This expanded collection takes you on a journey through the strange, surprising, and sometimes shocking tales that have shaped medicine as we know it.

Explore the peculiar, the profound, and the puzzling with entries like:

• Flying Babies? The unusual experiments of George Blonsky.

• Helium for Performance: The unexpected use of gas in an athletic enema.

• Poppies: Beautiful but Toxic – and Healthy? The dual nature of opium’s legacy.

• Mozart’s Chocolate Connection: A surprising link between Vesalius, Mozart, and everyone’s favorite treat.

• Urine: The Golden Elixir: Medicine’s strange fascination with this bodily fluid.

• Epilepsy: Divine or Demonic? How perceptions of the condition have evolved through the ages.

• Methamphetamine and Soldiers: The role of stimulants in wartime.

These new chapters join beloved stories from the first edition, bringing fresh insights into the weird and wonderful world of medical history. Each chapter is a standalone adventure, written in an accessible and engaging style that invites readers of all backgrounds to explore the quirks of medicine through the ages.

From Helen Keller’s crusade for the blind to Voltaire’s scandalous brew, this updated collection is perfect for curious minds, history buffs, and medical enthusiasts alike. Whether you’re intrigued by ancient remedies, strange experiments, or the lives of historical figures, Curiosities in Medicine: Alphabetically promises to entertain, enlighten, and inspire.

Prepare to laugh, gasp, and marvel at the stories that reveal the astonishing creativity, resilience, and oddities of the human pursuit of healing. This second edition will leave you questioning what you thought you knew about the history of medicine.

Curiosities in Medicine: Alphabetical – Where history meets the unexpected.